Search results for "Scoring system"

showing 10 items of 69 documents

Tackling invasive alien species in Europe II: threats and opportunities until 2020

2017

2nd Freshwater Invasives - Networking for Strategy II (FINS-II) Conference -- JUL 11-14, 2016 -- Zagreb, CROATIA Skora, Michal Edward/0000-0002-9121-1318; Groom, Quentin/0000-0002-0596-5376; Lukas, Juliane/0000-0003-3336-847X; Skora, Michal/0000-0002-9121-1318; Piria, Marina/0000-0001-6324-9282; Smith, Emily/0000-0003-2767-9933; Simonovic, Predrag/0000-0002-4819-4962; Pastorino, Paolo/0000-0002-0585-1168; Koutsikos, Nicholas/0000-0003-0680-4504; Vilizzi, Lorenzo/0000-0001-8103-885X; Dobrzycka-Krahel, Aldona/0000-0002-4252-895X; Tarkan, Ali Serhan/0000-0001-8628-0514 WOS: 000412582000002 Invasive alien species (IAS) are a significant and growing problem worldwide. In Europe, some aspects of …

0106 biological sciencesScoring systemStandardizationympäristöympäristöoikeusData managementBiosecurityympäristönhoitoECOSYSTEM SERVICES01 natural sciencesFRESH-WATER FISHenvironmental managementCITIZEN SCIENCEnon-native species ; legislation ; policy ; environmental management ; sequential rank voting ; scoring systemCitizen sciencesequential rank votingSDG 15 - Life on LandlainsäädäntöWarning systemCHALLENGESEcologyEnvironmental resource managementStakeholderPublic relationsnon-native speciesPolicyComputingMethodologies_DOCUMENTANDTEXTPROCESSING/dk/atira/pure/subjectarea/asjc/1100/1105non-native species; legislation; policy; environmental management; sequential rank voting; scoring systempolicyIMPACTSEnvironmental managementSequential rank votingCONSERVATIONLegislationNon-native species/dk/atira/pure/subjectarea/asjc/2300/2308LegislationBiologyManagement Monitoring Policy and Lawlegislation010603 evolutionary biology/dk/atira/pure/sustainabledevelopmentgoals/life_on_landEcology and EnvironmentGeneralLiterature_MISCELLANEOUSMANAGEMENTKNOWLEDGEnon-native specie14. Life underwatervieraslajit/dk/atira/pure/subjectarea/asjc/2300/2303ympäristöjohtaminenEcology Evolution Behavior and Systematicsbusiness.industry010604 marine biology & hydrobiologyscoring system13. Climate actionPrivate propertyta1181BIODIVERSITYbusiness
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12q14.3 microdeletion involving HMGA2 gene cause a Silver-Russell syndrome-like phenotype: a case report and review of the literature

2020

Abstract Background Silver-Russell Syndrome (SRS) is a genetic disorder characterized by intrauterine and postnatal growth restriction and normal head circumference with consequent relative macrocephaly. Addictional findings are protruding forehead in early life, body asymmetry (of upper and lower limbs) and substantial feeding difficulties. Although several genetic mechanisms that cause the syndrome are known, more than 40% of patients with a SRS-like phenotype remain without an etiological diagnosis. In the last few years, different clinical reports have suggested that mutations or deletions of the HMGA2 gene can be responsible for a SRS-like phenotype in patients with negative results of…

0301 basic medicineMaleCase Report030105 genetics & heredityBioinformaticsHMGA2 gene03 medical and health sciencesHMGA2parasitic diseasesmedicineHumansGeneChromosome 12biologybusiness.industrySilver–Russell syndromeNetchine-Harbison clinical scoring systemHMGA2 Proteinlcsh:RJ1-570Genetic disorderlcsh:PediatricsFailure to thrivemedicine.diseasePhenotypeSilver-Russell Syndrome030104 developmental biologyPhenotypeSettore MED/03 - Genetica MedicaChild PreschoolFailure to thriveEtiologybiology.proteinmedicine.symptombusinessGene DeletionItalian Journal of Pediatrics
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Phenotypic and functional characterization of neutrophils and monocytes from patients with myelodysplastic syndrome by flow cytometry.

2016

Myelodysplastic syndrome (MDS) is a clonal stem cell disorder frequently associated with inefficient granulopoiesis showing dysplastic polymorphonuclear neutrophils (PMNs). To assess PMN functionality in MDS in a clinical routine setting, 30 MDS patients and ten healthy volunteers were analyzed for PMN and monocyte phenotype and function (degranulation, CD62L shedding, oxidative burst and phagocytosis) upon stimulation with lipopolysaccharide by multi-color flow cytometry (MCFC). Our data show a heterogeneous pattern for CD66, CD16 and CD64 expression on PMNs of MDS patients. CD62L shedding rate and CD66 degranulation were reduced. Interestingly, we detected correlations between the WHO ada…

0301 basic medicineMaleCell DegranulationNeutrophilsImmunologyCell SeparationBiologyGranulopoiesisCell DegranulationMonocytesFlow cytometryImmunophenotyping03 medical and health sciences0302 clinical medicineMonitoring ImmunologicmedicineHumans610 Medicine & healthAgedMonitoring PhysiologicCD64Aged 80 and overCD11b Antigenmedicine.diagnostic_testMyelodysplastic syndromesMonocyteReceptors IgGDegranulationhemic and immune systemsMiddle Agedmedicine.diseaseFlow CytometryPrognosis030104 developmental biologymedicine.anatomical_structureInternational Prognostic Scoring SystemMyelodysplastic SyndromesImmunologyFemale030215 immunologyCellular immunology
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Semiquantitative evaluation of lymph-vascular space invasion in patients affected by endometrial cancer: Prognostic and clinical implications.

2020

Objectives: The interpretation of lymph-vascular space invasion (LVSI) is usually qualitative, as presence or absence. The aim of this study is to investigate the prognostic role of LVSI in patients affected by endometrial cancer, when evaluated with a semiquantitative analysis. Methods: This retrospective multicentre study enrolled patients who received a histologically confirmed diagnosis of endometrial cancer. The assessment of LVSI was semiquantitative in accordance with the three-tiered scoring system (absent, focal and diffuse). Results: Among 1258 patients with surgical-stage endometrial cancer, LVSI has been found in 32.8% of cases (n = 412), whose 12.7% (n = 160) were focal, and 20…

0301 basic medicineOncologyCancer Researchmedicine.medical_specialtyScoring systemLymph node metastasis03 medical and health sciences0302 clinical medicineEndometrial cancerRecurrenceRisk FactorsInternal medicinemedicineHumansIn patientLVSIGrading (tumors)business.industryEndometrial cancerNodal metastasisMiddle Agedmedicine.diseaseLymph-vascular space invasionPrognosisSurvival AnalysisEndometrial NeoplasmsVascular space030104 developmental biologySettore MED/40 - GINECOLOGIA E OSTETRICIAOncology030220 oncology & carcinogenesisLymphatic MetastasisFemaleLymphbusinessEuropean journal of cancer (Oxford, England : 1990)
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Outcome of liver transplantation for hepatopulmonary syndrome: a Eurotransplant experience.

2019

Hepatopulmonary syndrome (HPS) is a pulmonary vascular complication of liver disease that affects up to 30% of patients with cirrhosis [1]. Intrapulmonary vascular dilatations and shunts result in gas exchange abnormalities, ranging from elevated alveolar-arterial oxygen gradients with no hypoxemia to very severe hypoxemia [1, 2]. Currently, liver transplantation (LT) is the only treatment option [3]. The Model for End-Stage Liver Disease (MELD) is a scoring system for assessing liver disease severity that has been validated to predict the 3-months waitlist mortality, and is used by Eurotransplant for prioritising allocation of liver transplants [4]. Footnotes This manuscript has recently b…

0301 basic medicinePulmonary and Respiratory MedicineRiskScoring systemmedicine.medical_treatmentMedizinVascular complicationLiver transplantationEnd Stage Liver Disease03 medical and health sciences0302 clinical medicineSevere hypoxemiaNothingMedicineHumansRegistriesProportional Hazards ModelsRetrospective Studiesbusiness.industryConflict of interestTreatment optionsLiver TransplantationEuropeOxygen030104 developmental biologyTreatment OutcomeLaw030211 gastroenterology & hepatologybusinessProduction teamHepatopulmonary SyndromeThe European respiratory journal
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Smear layer removal evaluation of different protocol of Bio Race file and XP- endo Finisher file in corporation with EDTA 17% and NaOCl.

2017

Background The aim of the present study was to compare the amount of the smear layer remaining in prepared root canals with different protocols of Bio RaCe files and XP-endo Finisher file (XPF) in association with 17% EDTA and sodium hypochlorite solution. Material and Methods A total of 68 extracted single-rooted teeth were randomly divided into 4 experimental groups (n=14) and two control groups (n=6). The root canals were prepared with Bio RaCe files (FKG Dentaire, Switzerland) using the crown-down technique based on manufacturer's instructions and irrigated according to the following irrigation techniques: Group 1: XPF with 2 mL of 2.5% NaOCl for 1 minute. Group 2:, XPF with 1 mL of 17%…

0301 basic medicineScoring systemPost hocRoot canalmedicine.medical_treatmentSmear layerDentistryNegative controlPositive controlcomputer.software_genreOperative Dentistry and Endodontics03 medical and health scienceschemistry.chemical_compound0302 clinical medicinemedicineGeneral DentistrySalineMathematicsbusiness.industryResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]030104 developmental biologymedicine.anatomical_structurechemistrySodium hypochloriteUNESCO::CIENCIAS MÉDICASOperating systembusinesscomputerJournal of clinical and experimental dentistry
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Metabolic signatures across the full spectrum of non-alcoholic fatty liver disease.

2022

Funder: European Commission

ALTtype 2 diabetes mellitusROC receiving operator characteristicaspartate aminotransferaseHSDLDL low-density lipoproteinUHPLC ultrahigh-performance liquid chromatographyROCHCCNon-alcoholic steatohepatitisGCPCANASHGastroenterology2-HB 2-hydroxybutanoic acid; 3-HB 3-hydroxybutanoic acid; ALT alanine aminotransferase; AST aspartate aminotransferase; CE cholesterol ester; Cer ceramide; FFA free fatty acid; FLIP Fatty Liver Inhibition of Progression; Fibrosis; GC gas chromatography; HCC hepatocellular carcinoma; HSD honest significant difference; LC lipid cluster; LDL low-density lipoprotein; LM lipid and metabolite; LMC lipid metabolite and clinical variable; LPC lysophosphatidylcholine; Lipidomics; Mass spectrometry; Metabolomics; NAFL non-alcoholic fatty liver; NAFLD non-alcoholic fatty liver disease; NAS NASH activity score; NASH non-alcoholic steatohepatitis; NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network; NRR non-rejection rate; Non-alcoholic steatohepatitis; PC(O) ether PC; PC phosphatidylcholine; PCA principal component analysis; PE phosphatidylethanolamine; QTOFMS quadrupole-time-of-flight mass spectrometry; ROC receiving operator characteristic; SAF steatosis activity and fibrosis; SM sphingomyelin; T2DM type 2 diabetes mellitus; TG triacylglycerol; UHPLC ultrahigh-performance liquid chromatographySAFSAF steatosis activity and fibrosisLM lipid and metabolitehonest significant differenceHSD honest significant differenceTG triacylglycerolnon-rejection ratecholesterol esterPCPEGC gas chromatographyfree fatty acidFLIPNASH non-alcoholic steatohepatitisNIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkBIOMARKERST2DMPE phosphatidylethanolamineLDLlipidNAFLDFFA free fatty acid2-HBMetabolomicsNAFL non-alcoholic fatty liverLMCphosphatidylcholineScience & TechnologySM sphingomyelinGastroenterology & HepatologyMass spectrometryactivitynutritional and metabolic diseasesT2DM type 2 diabetes mellitusACIDSreceiving operator characteristicdigestive system diseasesquadrupole-time-of-flight mass spectrometryLC lipid clusterlow-density lipoproteinNAS2-HB 2-hydroxybutanoic acidNAS NASH activity scoreQTOFMSether PCNRRSCORING SYSTEMprincipal component analysisgas chromatographyLC2-hydroxybutanoic acidPROGRESSIONAST aspartate aminotransferaseLMPC phosphatidylcholinePC(O)MARKERSUHPLCsteatosisTOOLImmunology and AllergyINSULIN-RESISTANCECerSMFatty Liver Inhibition of Progressionhepatocellular carcinoma2-HB 2-hydroxybutanoic acid NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network NRR non-rejection rate Non-alcoholic steatohepatitis PC(O) ether PC PC phosphatidylcholine PCA principal component analysis PE phosphatidylethanolamine QTOFMS quadrupole-time-of-flight mass spectrometry ROC receiving operator characteristic SAF steatosis activity and fibrosis SM T2DM type 2 diabetes mellitus TG triacylglycerol UHPLC ultrahigh-performance liquid chromatographyultrahigh-performance liquid chromatographyCELPC3-HBNAFLnon-alcoholic fatty liverTGtriacylglycerolNRR non-rejection rateLife Sciences & BiomedicineNAFLD non-alcoholic fatty liver diseaseFLIP Fatty Liver Inhibition of Progressionalanine aminotransferasemetaboliteCer ceramideCE cholesterol estersphingomyelinlysophosphatidylcholineand fibrosisALT alanine aminotransferaseInternal MedicineceramideNational Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkAST3-HB 3-hydroxybutanoic acidQTOFMS quadrupole-time-of-flight mass spectrometryPCA principal component analysisLPC lysophosphatidylcholineHepatologynon-alcoholic fatty liver diseaseand clinical variablePC(O) ether PC3-hydroxybutanoic acidFibrosisNASH activity scoreNIDDK NASH-CRNlipid clusterlipid and metabolitephosphatidylethanolamineLipidomicsLMC lipid metabolite and clinical variableFFAHCC hepatocellular carcinomaJHEP reports : innovation in hepatology
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Multirotations-CT und ARDS

2001

Purpose Aim of the study was to investigate alveolar inspiration and expiration using multiscan CT. Results of a visual assessment using a scoring system were compared with density ranges known to represent alveolar ventilation best. Method Pigs were examined before and after lavage-induced ARDS. All animals were examined using dynamic multiscan CT. The visual assessment was done by a scoring system proposed by Gattinoni. The results were compared with planimetric determination of defined density ranges. Results In the healthy lung, the visual analysis showed higher scores at lower airway pressures with a marked gradient, whereas at higher pressures neither opacities nor gradients were obse…

ARDSScoring systemLungAirway pressuresbusiness.industryAcute respiratory distressrespiratory systemmedicine.diseaserespiratory tract diseasesLung densitymedicine.anatomical_structureMedicineRadiology Nuclear Medicine and imagingExpirationTomographybusinessNuclear medicineDer Radiologe
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Ten Years of Simultaneous Pancreas-Kidney Transplantation: A Retrospective Single-Center Analysis of Prospectively Obtained Data

2011

Simultaneous pancreas-kidney transplantation (SPK) is a standardized and life-saving procedure for a patient suffering from both insulin-dependent diabetes mellitus type 1 (IDDM 1) and end-stage diabetic nephropathy. To expand the donor pool and to determine the influence of the preprocurement pancreas suitability scoring system (P-PASS) on pancreas graft survival we retrospectively analyzed our data on SPK.From 1999 to 2010 we performed 55 SPKs, using systemic-enteric drainage as surgical approach. The immunosuppressive therapy was induced with basiliximab; maintenance therapy was based on tacrolimus, mycophenolate mofetil, and steroids. Data were prospectively obtained, analyzed, and corr…

AdultGraft RejectionMalemedicine.medical_specialtyScoring systemCell SurvivalSingle CenterBody Mass IndexDiabetic nephropathyDiabetes mellitusmedicineHumansDiabetic NephropathiesProspective StudiesDonor poolRetrospective StudiesTransplantationbusiness.industryGraft SurvivalSimultaneous pancreas kidney transplantationMiddle Agedmedicine.diseaseKidney TransplantationSurgeryTransplantationDiabetes Mellitus Type 1Treatment Outcomemedicine.anatomical_structureFemaleSurgeryPancreas TransplantationPancreasbusinessImmunosuppressive AgentsTransplantation Proceedings
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Refined cytogenetic-risk categorization for overall and leukemia-free survival in primary myelofibrosis: a single center study of 433 patients.

2011

We have previously identified sole +9, 13q- or 20q-, as 'favorable' and sole +8 or complex karyotype as 'unfavorable' cytogenetic abnormalities in primary myelofibrosis (PMF). In this study of 433 PMF patients, we describe additional sole abnormalities with favorable (chromosome 1 translocations/duplications) or unfavorable (-7/7q-) prognosis and also show that other sole or two abnormalities that do not include i(17q), -5/5q-, 12p-, inv(3) or 11q23 rearrangement are prognostically aligned with normal karyotype, which is prognostically favorable. These findings were incorporated into a refined two-tired cytogenetic-risk stratification: unfavorable and favorable karyotype. The respective 5-y…

AdultMaleRiskCancer Researchmedicine.medical_specialtyPathologyAdolescentChromosomal translocationmyelofibrosisGastroenterologycytogeneticsDisease-Free SurvivalSettore MED/15 - Malattie Del SangueInternal medicineComplex KaryotypemedicineHumansMyelofibrosisAgedAged 80 and overChromosome AberrationsLeukemiaHematologyPlatelet Countbusiness.industryHazard ratioKaryotypeHematologyMiddle AgedPrognosismedicine.diseaseConfidence intervalkaryotypeOncologyPrimary MyelofibrosisInternational Prognostic Scoring SystemKaryotypingOriginal ArticleFemalemyeloproliferativebusiness
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